Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning formatIsbn:Softcover - 9781461372387 University of Kansas

University of Kansas

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München: Verlag Lothar Borowsky

It became widely recognized during the beginning of this century that the pyrogenicity of many microbial infections may be associated with endotoxins

Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning formatIsbn:Softcover - 9781461372387 University of KansasWhen first introduced, antisense oligonucleotides were hailed as the long awaited magic bullet that would provide an unprecedented level of specificity in controlling gene expression. Following this initial enthusiasm, antisense oligonucleotides have been maligned as nonspecific, toxic, and essentially useless. However, application of antisense oligonucleotide technology in the nervous system stands apart from the use of this technique in peripheral